Ensembl ENSG00000105989 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22413 (HomologyMapper) WNT2 Ensembl ENSG00000158955 Ensembl ENSG00000188064 Ensembl ENSG00000108379 Calcium Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14368 (HomologyMapper) FZD6 Ensembl ENSG00000111186 Ensembl ENSG00000174804 Ensembl ENSG00000180340 Homo sapiens Ensembl ENSG00000155760 Wnt Signaling in Kidney Disease This pathway was inferred from Mus musculus pathway "Wnt Signaling in Kidney Disease", WP3857 revision 90183, with a 97.0% conversion rate. (HomologyMapper) This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin transcription. The complex of Nphp2 and Nphp3 seem to help facilitate the process by controlling the Wnt signaling. Bergmann, et al. (2008) showed that Nphp3 deficiency in Xenopus resulted to planar cell polarity defects. (WikiPathways-description) Ensembl ENSG00000188763 Ensembl ENSG00000113971 HMDB HMDB00464 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14371 (HomologyMapper) FZD9 Ensembl ENSG00000168036 Ensembl ENSG00000177283 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26419 (HomologyMapper) MAPK8 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14366 (HomologyMapper) FZD4 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14370 (HomologyMapper) FZD8 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000032558 (HomologyMapper) NPHP3 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13544 (HomologyMapper) DVL3 Ensembl ENSG00000157240 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13542 (HomologyMapper) DVL1 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22415 (HomologyMapper) WNT3 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22419 (HomologyMapper) WNT5B Ensembl ENSG00000002745 Ensembl ENSG00000154764 Ensembl ENSG00000169884 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22422 (HomologyMapper) WNT7B Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14365 (HomologyMapper) FZD3 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22411 (HomologyMapper) WNT11 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22416 (HomologyMapper) WNT3A Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14362 (HomologyMapper) FZD1 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26420 (HomologyMapper) MAPK9 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13544 (HomologyMapper) DVL3 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14366 (HomologyMapper) FZD4 Ensembl ENSG00000135925 Ensembl ENSG00000125084 Ensembl ENSG00000162552 Ensembl ENSG00000154342 Ensembl ENSG00000134245 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22409 (HomologyMapper) WNT10A Ensembl ENSG00000085741 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14369 (HomologyMapper) FZD7 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14365 (HomologyMapper) FZD3 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000030201 (HomologyMapper) LRP6 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14362 (HomologyMapper) FZD1 Ensembl ENSG00000115596 Ensembl ENSG00000114251 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:57265 (HomologyMapper) FZD2 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22420 (HomologyMapper) WNT6 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22421 (HomologyMapper) WNT7A Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14369 (HomologyMapper) FZD7 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22417 (HomologyMapper) WNT4 Ensembl ENSG00000119509 Ensembl ENSG00000162337 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22414 (HomologyMapper) WNT2B Ensembl ENSG00000070018 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14367 (HomologyMapper) FZD5 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22412 (HomologyMapper) WNT9B Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22410 (HomologyMapper) WNT10B Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13543 (HomologyMapper) DVL2 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000006932 (HomologyMapper) CTNNB1 Ensembl ENSG00000163251 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:57265 (HomologyMapper) FZD2 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14367 (HomologyMapper) FZD5 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14368 (HomologyMapper) FZD6 Ensembl ENSG00000004975 Ensembl ENSG00000161202 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14371 (HomologyMapper) FZD9 Ensembl ENSG00000164930 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26414 (HomologyMapper) MAPK10 Ensembl ENSG00000104290 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22418 (HomologyMapper) WNT5A Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13542 (HomologyMapper) DVL1 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22408 (HomologyMapper) WNT1 Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000028344 (HomologyMapper) INVS Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000024913 (HomologyMapper) LRP5 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13543 (HomologyMapper) DVL2 Ensembl ENSG00000050748 Ensembl ENSG00000107404 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14370 (HomologyMapper) FZD8 Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:93735 (HomologyMapper) WNT16 Ensembl ENSG00000107643 No homologues found for original id En:ENSMUSG00000007815 (HomologyMapper) Rhoa Ensembl ENSG00000109339