Ensembl
ENSG00000105989
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22413 (HomologyMapper)
WNT2
Ensembl
ENSG00000158955
Ensembl
ENSG00000188064
Ensembl
ENSG00000108379
Calcium
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14368 (HomologyMapper)
FZD6
Ensembl
ENSG00000111186
Ensembl
ENSG00000174804
Ensembl
ENSG00000180340
Homo sapiens
Ensembl
ENSG00000155760
Wnt Signaling in Kidney Disease
This pathway was inferred from Mus musculus pathway "Wnt Signaling in Kidney Disease", WP3857 revision 90183, with a 97.0% conversion rate. (HomologyMapper)
This pathway is modeled after Figure 5 of the article "Glomerulocystic kidney disease" (Bissler, et al. 2010). The gene product Wnt signals two different paths titled canonical and non-canonical. The non-canonical path is mediated by the membrane bound protein Disheveled (Dvl) which then controls the planar cell Polarity. The canonical path on the other hand is mediated by the cytoplasmic protein Disheveled (Dvl) and then is effected through b-catenin transcription. The complex of Nphp2 and Nphp3 seem to help facilitate the process by controlling the Wnt signaling. Bergmann, et al. (2008) showed that Nphp3 deficiency in Xenopus resulted to planar cell polarity defects. (WikiPathways-description)
Ensembl
ENSG00000188763
Ensembl
ENSG00000113971
HMDB
HMDB00464
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14371 (HomologyMapper)
FZD9
Ensembl
ENSG00000168036
Ensembl
ENSG00000177283
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26419 (HomologyMapper)
MAPK8
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14366 (HomologyMapper)
FZD4
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14370 (HomologyMapper)
FZD8
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000032558 (HomologyMapper)
NPHP3
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13544 (HomologyMapper)
DVL3
Ensembl
ENSG00000157240
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13542 (HomologyMapper)
DVL1
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22415 (HomologyMapper)
WNT3
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22419 (HomologyMapper)
WNT5B
Ensembl
ENSG00000002745
Ensembl
ENSG00000154764
Ensembl
ENSG00000169884
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22422 (HomologyMapper)
WNT7B
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14365 (HomologyMapper)
FZD3
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22411 (HomologyMapper)
WNT11
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22416 (HomologyMapper)
WNT3A
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14362 (HomologyMapper)
FZD1
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26420 (HomologyMapper)
MAPK9
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13544 (HomologyMapper)
DVL3
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14366 (HomologyMapper)
FZD4
Ensembl
ENSG00000135925
Ensembl
ENSG00000125084
Ensembl
ENSG00000162552
Ensembl
ENSG00000154342
Ensembl
ENSG00000134245
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22409 (HomologyMapper)
WNT10A
Ensembl
ENSG00000085741
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14369 (HomologyMapper)
FZD7
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14365 (HomologyMapper)
FZD3
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000030201 (HomologyMapper)
LRP6
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14362 (HomologyMapper)
FZD1
Ensembl
ENSG00000115596
Ensembl
ENSG00000114251
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:57265 (HomologyMapper)
FZD2
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22420 (HomologyMapper)
WNT6
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22421 (HomologyMapper)
WNT7A
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14369 (HomologyMapper)
FZD7
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22417 (HomologyMapper)
WNT4
Ensembl
ENSG00000119509
Ensembl
ENSG00000162337
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22414 (HomologyMapper)
WNT2B
Ensembl
ENSG00000070018
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14367 (HomologyMapper)
FZD5
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22412 (HomologyMapper)
WNT9B
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22410 (HomologyMapper)
WNT10B
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13543 (HomologyMapper)
DVL2
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000006932 (HomologyMapper)
CTNNB1
Ensembl
ENSG00000163251
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:57265 (HomologyMapper)
FZD2
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14367 (HomologyMapper)
FZD5
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14368 (HomologyMapper)
FZD6
Ensembl
ENSG00000004975
Ensembl
ENSG00000161202
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14371 (HomologyMapper)
FZD9
Ensembl
ENSG00000164930
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26414 (HomologyMapper)
MAPK10
Ensembl
ENSG00000104290
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22418 (HomologyMapper)
WNT5A
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13542 (HomologyMapper)
DVL1
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22408 (HomologyMapper)
WNT1
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000028344 (HomologyMapper)
INVS
Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000024913 (HomologyMapper)
LRP5
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13543 (HomologyMapper)
DVL2
Ensembl
ENSG00000050748
Ensembl
ENSG00000107404
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14370 (HomologyMapper)
FZD8
Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:93735 (HomologyMapper)
WNT16
Ensembl
ENSG00000107643
No homologues found for original id En:ENSMUSG00000007815 (HomologyMapper)
Rhoa
Ensembl
ENSG00000109339